|
ST8SIA6-AS1
|
Malignant neoplasm of breast
|
0.020 |
Biomarker |
BEFREE |
Together, our data suggest that ST8SIA6-AS1 plays an important role in the occurrence and development of BC and may therefore serve as a promising therapeutic target.
|
31784750 |
2019 |
|
ST8SIA6-AS1
|
Neoplasms
|
0.020 |
AlteredExpression |
BEFREE |
The results of the in vivo studies indicated that upregulation of ST8SIA6-AS1 promoted xenograft tumour growth of BC.
|
31784750 |
2019 |
|
ST8SIA6-AS1
|
Neoplasms
|
0.020 |
Biomarker |
BEFREE |
Notably, targeting APAL inhibits the growth of breast and lung cancer xenografts in vivo (MCF-7 xenografts: mean tumor weight, control =0.18 g [SD = 0.03] vs APAL LNA = 0.07 g [SD = 0.02], P < 0.001, n = 8 mice per group; A549 xenografts: mean tumor weight control = 0.36 g [SD = 0.10] vs APAL LNA = 0.10 g [SD = 0.04], P < 0.001, n = 9 mice per group) and the survival of patient-derived breast cancer organoids in three-dimensional cultures.
|
31286138 |
2019 |
|
ST8SIA6-AS1
|
Breast Carcinoma
|
0.020 |
Biomarker |
BEFREE |
Together, our data suggest that ST8SIA6-AS1 plays an important role in the occurrence and development of BC and may therefore serve as a promising therapeutic target.
|
31784750 |
2019 |
|
ST8SIA6-AS1
|
Malignant neoplasm of breast
|
0.020 |
AlteredExpression |
BEFREE |
Taken together, KLHDC7B and STAR1 are both overexpressed in breast cancer and significantly associated with gene modulation activity in the interferon signaling pathway during breast tumorigenesis.
|
30150751 |
2018 |
|
ST8SIA6-AS1
|
Breast Carcinoma
|
0.020 |
AlteredExpression |
BEFREE |
Taken together, KLHDC7B and STAR1 are both overexpressed in breast cancer and significantly associated with gene modulation activity in the interferon signaling pathway during breast tumorigenesis.
|
30150751 |
2018 |
|
ST8SIA6-AS1
|
Malignant Neoplasms
|
0.010 |
Biomarker |
BEFREE |
Overexpressing APAL accelerates cancer cell cycle progression, promotes proliferation and inhibits chemotherapy-induced apoptosis.
|
31286138 |
2019 |
|
ST8SIA6-AS1
|
Tumor Cell Invasion
|
0.010 |
Biomarker |
BEFREE |
LncRNA ST8SIA6-AS1 promotes proliferation, migration and invasion in breast cancer through the p38 MAPK ssignalling pathway.
|
31784750 |
2019 |
|
ST8SIA6-AS1
|
Primary malignant neoplasm
|
0.010 |
Biomarker |
BEFREE |
Overexpressing APAL accelerates cancer cell cycle progression, promotes proliferation and inhibits chemotherapy-induced apoptosis.
|
31286138 |
2019 |
|
ST8SIA6-AS1
|
Carcinogenesis
|
0.010 |
AlteredExpression |
BEFREE |
Taken together, KLHDC7B and STAR1 are both overexpressed in breast cancer and significantly associated with gene modulation activity in the interferon signaling pathway during breast tumorigenesis.
|
30150751 |
2018 |