Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0014772
Disease: Red Blood Cell Count measurement
Red Blood Cell Count measurement
0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0023508
Disease: White Blood Cell Count procedure
White Blood Cell Count procedure
0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
Red cell distribution width determination
0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
RDW - Red blood cell distribution width result
0.100 GeneticVariation GWASCAT Leveraging Polygenic Functional Enrichment to Improve GWAS Power. 30595370

2019

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0524587
Disease: Mean Corpuscular Volume (result)
Mean Corpuscular Volume (result)
0.100 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010

2018

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
Finding of Mean Corpuscular Hemoglobin
0.100 GeneticVariation GWASCAT Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases. 29403010

2018

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
Red cell distribution width determination
0.100 GeneticVariation GWASCAT Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. 28957414

2017

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0524587
Disease: Mean Corpuscular Volume (result)
Mean Corpuscular Volume (result)
0.100 GeneticVariation GWASCAT Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis. 28017375

2017

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
Finding of Mean Corpuscular Hemoglobin
0.100 GeneticVariation GWASCAT IDENTIFYING GENETIC ASSOCIATIONS WITH VARIABILITY IN METABOLIC HEALTH AND BLOOD COUNT LABORATORY VALUES: DIVING INTO THE QUANTITATIVE TRAITS BY LEVERAGING LONGITUDINAL DATA FROM AN EHR. 27897004

2017

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
RDW - Red blood cell distribution width result
0.100 GeneticVariation GWASCAT Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. 28957414

2017

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0023508
Disease: White Blood Cell Count procedure
White Blood Cell Count procedure
0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0200633
Disease: Neutrophil count (procedure)
Neutrophil count (procedure)
0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0200638
Disease: Eosinophil count procedure
Eosinophil count procedure
0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0200641
Disease: Blood basophil count (lab test)
Blood basophil count (lab test)
0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
Platelet mean volume determination (procedure)
0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0206161
Disease: Reticulocyte count (procedure)
Reticulocyte count (procedure)
0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
Red cell distribution width determination
0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0524587
Disease: Mean Corpuscular Volume (result)
Mean Corpuscular Volume (result)
0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0857490
Disease: Granulocyte count
Granulocyte count
0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
Finding of Mean Corpuscular Hemoglobin
0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
RDW - Red blood cell distribution width result
0.100 GeneticVariation GWASCAT The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. 27863252

2016

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
Corpuscular Hemoglobin Concentration Mean
0.100 GeneticVariation GWASDB Seventy-five genetic loci influencing the human red blood cell. 23222517

2012

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.010 Biomarker BEFREE Together, the data indicate that ARKL1 is a negative regulator of Zp and EBV reactivation that acts by inhibiting Jun activity through a CK2β-mediated interaction.<b>IMPORTANCE</b> Epstein-Barr virus (EBV) maintains a life-long infection due to the ability to alternate between latent and lytic modes of replication and is associated with several types of cancer. 31341047

2019

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C0393591
Disease: AICARDI-GOUTIERES SYNDROME
AICARDI-GOUTIERES SYNDROME
0.010 Biomarker BEFREE Silencing of ARKL1 in the context of EBV-positive gastric carcinoma (AGS) cells, nasopharyngeal carcinoma (NPC43) cells, and B (M81) cells led to increased lytic protein expression, whereas overexpression inhibited BZLF1 expression. 31341047

2019

Entrez Id: 147339
Gene Symbol: C18orf25
C18orf25
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker BEFREE Together, the data indicate that ARKL1 is a negative regulator of Zp and EBV reactivation that acts by inhibiting Jun activity through a CK2β-mediated interaction.<b>IMPORTANCE</b> Epstein-Barr virus (EBV) maintains a life-long infection due to the ability to alternate between latent and lytic modes of replication and is associated with several types of cancer. 31341047

2019