Source: CURATED

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.550 Biomarker CTD_human Our data implicate PDK-1 and downstream components of the PDK-1 signaling pathway as promising therapeutic targets for the treatment of breast cancer. 24739482

2014
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.550 Biomarker CTD_human Our data implicate PDK-1 and downstream components of the PDK-1 signaling pathway as promising therapeutic targets for the treatment of breast cancer. 24739482

2014
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.550 GenomicAlterations CGI

Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma 		0.550 GenomicAlterations CGI

Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms 		0.310 Biomarker CTD_human Immunohistochemical analysis of PDK1 expression in breast cancer. 24739482

2014
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0079744
Disease: Diffuse Large B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma 		0.310 Biomarker CTD_human Critical role of PI3K signaling for NF-kappaB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells. 21173233

2011
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C1257931
Disease: Mammary Neoplasms, Human
Mammary Neoplasms, Human 		0.300 Biomarker CTD_human Immunohistochemical analysis of PDK1 expression in breast cancer. 24739482

2014
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C4704874
Disease: Mammary Carcinoma, Human
Mammary Carcinoma, Human 		0.300 Biomarker CTD_human Immunohistochemical analysis of PDK1 expression in breast cancer. 24739482

2014
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0018801
Disease: Heart failure
Heart failure 		0.300 Biomarker CTD_human PDK1 coordinates survival pathways and beta-adrenergic response in the heart. 19429709

2009
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.300 Biomarker CTD_human PDK1 coordinates survival pathways and beta-adrenergic response in the heart. 19429709

2009
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0023212
Disease: Left-Sided Heart Failure
Left-Sided Heart Failure 		0.300 Biomarker CTD_human PDK1 coordinates survival pathways and beta-adrenergic response in the heart. 19429709

2009
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0235527
Disease: Heart Failure, Right-Sided
Heart Failure, Right-Sided 		0.300 Biomarker CTD_human PDK1 coordinates survival pathways and beta-adrenergic response in the heart. 19429709

2009
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C1959583
Disease: Myocardial Failure
Myocardial Failure 		0.300 Biomarker CTD_human PDK1 coordinates survival pathways and beta-adrenergic response in the heart. 19429709

2009
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C1961112
Disease: Heart Decompensation
Heart Decompensation 		0.300 Biomarker CTD_human PDK1 coordinates survival pathways and beta-adrenergic response in the heart. 19429709

2009
Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0496956
Disease: Neoplasm of uncertain or unknown behavior of breast
Neoplasm of uncertain or unknown behavior of breast 		0.300 GenomicAlterations CGI

Entrez Id: 5170
Gene Symbol: PDPK1
PDPK1
CUI: C0858252
Disease: Breast adenocarcinoma
Breast adenocarcinoma 		0.300 GenomicAlterations CGI