Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0000880
Disease: Acanthamoeba Keratitis
Acanthamoeba Keratitis 		0.220 AlteredExpression BEFREE The aim of this study was to determine for the first time the expression of TLR2 and TLR4 in the lung of Acanthamoeba spp. infected mice using quantitative real-time polymerase chain reaction (Q-PCR) and immunohistochemical (IHC) staining.The Acanthamoeba spp. were isolated from a patient with Acanthamoeba keratitis (AK) (strain Ac 55) and from environmental samples of water from Malta Lake (Poznań, Poland - strain Ac 43). 26940205

2016
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0000880
Disease: Acanthamoeba Keratitis
Acanthamoeba Keratitis 		0.220 Biomarker BEFREE Results suggest that pathogenic species of Acanthamoeba activate TLR4 and induce production of CXCL2 in the Chinese hamster model of AK. 24633052

2014
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
CUI: C0000880
Disease: Acanthamoeba Keratitis
Acanthamoeba Keratitis 		0.220 Biomarker RGD Toll-like receptor 4 signalling pathway activation in a rat model of Acanthamoeba Keratitis. 21155840

2011