Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10014
Gene Symbol: HDAC5
HDAC5
CUI: C0001546
Disease: Adjustment Disorders
Adjustment Disorders
0.300 Biomarker CTD_human Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. 17988634

2007

Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
CUI: C0001546
Disease: Adjustment Disorders
Adjustment Disorders
0.020 Biomarker BEFREE The AjD CBT protocol specifically developed for this disorder has shown positive results when delivered face to face and through virtual reality. 31614596

2019

Entrez Id: 611
Gene Symbol: OPN1SW
OPN1SW
CUI: C0001546
Disease: Adjustment Disorders
Adjustment Disorders
0.020 Biomarker BEFREE The treatments were standard CBT protocols for post-traumatic stress disorder (PTSD), complicated grief (CG), or adjustment disorders (ADs), depending on each patient diagnosis. 29988491

2018

Entrez Id: 627
Gene Symbol: BDNF
BDNF
CUI: C0001546
Disease: Adjustment Disorders
Adjustment Disorders
0.010 AlteredExpression BEFREE Plasma Brain-Derived Neurotrophic Factor (BDNF) and serum cortisol levels in a sample of workers exposed to occupational stress and suffering from Adjustment Disorders. 31197968

2019

Entrez Id: 574411
Gene Symbol: MIR451A
MIR451A
CUI: C0001546
Disease: Adjustment Disorders
Adjustment Disorders
0.010 Biomarker BEFREE In this study, our aim was to investigate levels of macrophage migration inhibitory factor and its regulating microRNA-451a in patients with depression, anxiety, or stress and adjustment disorders who underwent mindfulness-based therapy or treatment as usual. 29373661

2018

Entrez Id: 4282
Gene Symbol: MIF
MIF
CUI: C0001546
Disease: Adjustment Disorders
Adjustment Disorders
0.010 AlteredExpression BEFREE In this study, our aim was to investigate levels of macrophage migration inhibitory factor and its regulating microRNA-451a in patients with depression, anxiety, or stress and adjustment disorders who underwent mindfulness-based therapy or treatment as usual. 29373661

2018

Entrez Id: 673
Gene Symbol: BRAF
BRAF
CUI: C0001546
Disease: Adjustment Disorders
Adjustment Disorders
0.010 GeneticVariation BEFREE Like in other non-pulmonary Langerhans cell proliferations, PLCH has recently been shown to harbour BRAF V600E mutations in a significant subset of cases, thus challenging the concept of PLCH being a reactive disorder. 28220299

2017

Entrez Id: 4597
Gene Symbol: MVD
MVD
CUI: C0001546
Disease: Adjustment Disorders
Adjustment Disorders
0.010 GeneticVariation BEFREE In this context, the distinctive role of a positive JAK2(V617F) mutation for the diagnosis of Ph- MPD was underscored, including entities with a low allele burden and the discrimination from reactive disorders (autoimmune myelofibrosis, reactive thrombocytosis). 19605821

2009

Entrez Id: 3717
Gene Symbol: JAK2
JAK2
CUI: C0001546
Disease: Adjustment Disorders
Adjustment Disorders
0.010 GeneticVariation BEFREE In this context, the distinctive role of a positive JAK2(V617F) mutation for the diagnosis of Ph- MPD was underscored, including entities with a low allele burden and the discrimination from reactive disorders (autoimmune myelofibrosis, reactive thrombocytosis). 19605821

2009

Entrez Id: 7054
Gene Symbol: TH
TH
CUI: C0001546
Disease: Adjustment Disorders
Adjustment Disorders
0.010 GeneticVariation BEFREE A significant variation in the prevalence of carriers of the TH-K3 allele (high for suicide attempters with adjustment disorders, P = 0.0023) and a tendency toward a variation of the TH-K1 allele (low among all suicide attempters, P = 0.046) was observed. 9335198

1997