Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1829
Gene Symbol: DSG2
DSG2
CUI: C0004779
Disease: Basal Cell Nevus Syndrome
Basal Cell Nevus Syndrome 		0.010 Biomarker BEFREE Using a mouse model of Gorlin syndrome (Ptc1<sup>+/lacZ</sup> mice), we found that overexpressing Dsg2 in the basal layer (K14-Dsg2/Ptc1<sup>+/lacZ</sup> mice) or the superficial epidermis (Inv-Dsg2/Ptc1<sup>+/lacZ</sup> mice) resulted in increased spontaneous BCC formation at 3 and 6 months, respectively. 30291846

2019