Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1421
Gene Symbol: CRYGD
CRYGD
CUI: C0005779
Disease: Blood Coagulation Disorders
Blood Coagulation Disorders
0.040 Biomarker BEFREE 4F-PCC is an effective but expensive treatment option for those requiring urgent reversal of vitamin K antagonist-induced coagulopathy. 31121073

2019

Entrez Id: 1421
Gene Symbol: CRYGD
CRYGD
CUI: C0005779
Disease: Blood Coagulation Disorders
Blood Coagulation Disorders
0.040 Biomarker BEFREE Dosing 4F-PCC using adjusted body weight in obese patients resulted in a significantly lower rate of coagulopathy reversal. 30460443

2019

Entrez Id: 1421
Gene Symbol: CRYGD
CRYGD
CUI: C0005779
Disease: Blood Coagulation Disorders
Blood Coagulation Disorders
0.040 Biomarker BEFREE 4F-PCC was administered 32 times in 26 patients for nonvitamin-K antagonist related coagulopathy (11 CAS and 21 liver dysfunction) and 47 administrations were in warfarin patients. 28604569

2017

Entrez Id: 1421
Gene Symbol: CRYGD
CRYGD
CUI: C0005779
Disease: Blood Coagulation Disorders
Blood Coagulation Disorders
0.040 Biomarker BEFREE These observations suggest that the efficacy of 4F-PCC is suboptimal to correct coagulopathy and hemostasis in patients with LD, who have high rates of in-hospital mortality due to sequelae of LD. 27628534

2017