Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 22992
Gene Symbol: KDM2A
KDM2A
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.060 PosttranslationalModification BEFREE Taken together, we demonstrate for the first time that TET2 is a direct repression target of KDM2A and reveal a novel mechanism by which KDM2A promotes DNA methylation and breast cancer progression via the inhibition of a DNA demethylase. 28785073

2017
Entrez Id: 22992
Gene Symbol: KDM2A
KDM2A
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.060 Biomarker BEFREE SF-KDM2A was more abundant than full-length KDM2A in a subset of breast cancers. 28350064

2017
Entrez Id: 22992
Gene Symbol: KDM2A
KDM2A
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.060 Biomarker BEFREE Knockdown of KDM2A in breast cancer cells reduced proliferation but not viability. 27029061

2016
Entrez Id: 22992
Gene Symbol: KDM2A
KDM2A
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.060 Biomarker BEFREE Furthermore, our data indicate that the short isoform of KDM2A has oncogenic potential and functions as an oncogenic isoform in a subset of breast cancers. 26207617

2016
Entrez Id: 22992
Gene Symbol: KDM2A
KDM2A
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.060 Biomarker BEFREE We detected KDM2A in breast cancer tissues irrespective of their estrogen receptor, progesterone receptor, and HER2 status, including triple-negative cancer tissues. 26416883

2015
Entrez Id: 22992
Gene Symbol: KDM2A
KDM2A
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast 		0.060 AlteredExpression BEFREE Here we show that KDM2A is strongly expressed in myoepithelial cells (MEPC) in breast cancer tissues by immunohistochemistry. 25029110

2014