×
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
Uterine Cervical Neoplasm
0.510
GeneticVariation
BEFREE
A large proportion of these tumors (39%) harbored somatic activating FGFR3 mutations, identical to those associated with skeletal dysplasia syndromes and bladder and cervical neoplasms .
15772091 2005
×
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
Uterine Cervical Neoplasm
0.510
Biomarker
CTD_human
×
Entrez Id: 2261
Gene Symbol: FGFR3
FGFR3
Uterine Cervical Neoplasm
0.510
CausalMutation
CGI
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Cervical Neoplasm
0.470
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Cervical Neoplasm
0.470
AlteredExpression
BEFREE
In conclusion, our findings demonstrate that a combined strategy of co-expressed E6-specific siRNA and p53 synergistically and more effectively suppressed cervical tumor growth when compared with single treatment.
23435374 2013
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Cervical Neoplasm
0.470
Biomarker
LHGDN
Enhanced specificity of the p53 family proteins-based adenoviral gene therapy in uterine cervical cancer cells with E2F1-responsive promoters.
17012841 2006
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Cervical Neoplasm
0.470
Biomarker
BEFREE
HPV18 E6 and E7 genes affect cell cycle, pRB and p53 of cervical tumor cells and represent prominent candidates for intervention by use peptide nucleic acids (PNAs).
15145519 2004
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Cervical Neoplasm
0.470
AlteredExpression
LHGDN
p53, Bcl-2, PCNA expression, and apoptotic rates during cervical tumorigenesis.
15033825 2003
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Cervical Neoplasm
0.470
GeneticVariation
BEFREE
The implication of the codon 72 polymorphism of p53 in cervical tumor remains controversial.
12821336 2003
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Cervical Neoplasm
0.470
Biomarker
LHGDN
Relationship between HPV typing and abnormality of G1 cell cycle regulators in cervical neoplasm.
14675665 2003
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Cervical Neoplasm
0.470
Biomarker
BEFREE
It can be concluded, that in the Egyptian population, p53 immunoreactivity appears to be an early event in cervical neoplasm , and seems to play an important role together with other cell regulatory proteins in the process of carcinogenesis, which could be different between sqcc and adenocarcinoma.
10607922 1999
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
Uterine Cervical Neoplasm
0.470
CausalMutation
CGI
×
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
Uterine Cervical Neoplasm
0.410
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
Uterine Cervical Neoplasm
0.410
Biomarker
CTD_human
Biological significance and therapeutic implication of resveratrol-inhibited Wnt, Notch and STAT3 signaling in cervical cancer cells.
25061499 2014
×
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1
Uterine Cervical Neoplasm
0.410
GeneticVariation
BEFREE
Cytoplasmic/nuclear expression without mutation of exon 3 of the beta-catenin gene is frequent in the development of the neoplasm of the uterine cervix .
11520139 2001
×
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
Uterine Cervical Neoplasm
0.400
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
Uterine Cervical Neoplasm
0.400
GeneticVariation
CLINVAR
Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.
26619011 2016
×
Entrez Id: 2475
Gene Symbol: MTOR
MTOR
Uterine Cervical Neoplasm
0.400
Biomarker
CTD_human
Expression of an activated mammalian target of rapamycin in adenocarcinoma of the cervix: A potential biomarker and molecular target therapy.
18058806 2008
×
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
Uterine Cervical Neoplasm
0.400
CausalMutation
CGI
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Uterine Cervical Neoplasm
0.320
Biomarker
CTD_human
PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling.
26432044 2015
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Uterine Cervical Neoplasm
0.320
AlteredExpression
LHGDN
Expression of IP-10 related to angiogenesis in uterine cervical cancers.
17505511 2007
×
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
Uterine Cervical Neoplasm
0.320
AlteredExpression
LHGDN
Vascular endothelial growth factor, matrix metalloproteinases, and cyclooxygenase-2 influence prognosis of uterine cervical cancer in young women.
17671679 2007
×
Entrez Id: 332
Gene Symbol: BIRC5
BIRC5
Uterine Cervical Neoplasm
0.310
Biomarker
CTD_human
PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling.
26432044 2015
×
Entrez Id: 4609
Gene Symbol: MYC
MYC
Uterine Cervical Neoplasm
0.310
Biomarker
CTD_human
PIAS3, SHP2 and SOCS3 Expression patterns in Cervical Cancers: Relevance with activation and resveratrol-caused inactivation of STAT3 signaling.
26432044 2015
×
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
Uterine Cervical Neoplasm
0.310
GeneticVariation
BEFREE
Our cervical tumor mutational landscape shows that most mutations are found in PIK3CA (E545K , E542K ) and KRAS (G12D , G13D ) and others in FBXW7 (R465C , R505G , R479Q ).
26155992 2015