Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6689
Gene Symbol: SPIB
SPIB
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.620 GeneticVariation GWASCAT International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways. 26394269

2015
Entrez Id: 6689
Gene Symbol: SPIB
SPIB
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.620 GeneticVariation BEFREE We fine mapped two primary biliary cirrhosis (PBC) risk loci, CLEC16A (C-type lectin domain family 16 member A)-suppressor of cytokine signaling 1 (SOCS1) and Spi-B protein (SPIB) and sequenced a locus, sialic acid acetylesterase (SIAE), proposed to harbor autoimmunity-associated mutations. 22257840

2012
Entrez Id: 6689
Gene Symbol: SPIB
SPIB
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.620 GeneticVariation GWASCAT Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. 21399635

2011
Entrez Id: 6689
Gene Symbol: SPIB
SPIB
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.620 GeneticVariation GWASDB Genome-wide association study identifies 12 new susceptibility loci for primary biliary cirrhosis. 21399635

2011
Entrez Id: 6689
Gene Symbol: SPIB
SPIB
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.620 Biomarker BEFREE To examine the genetics of susceptibility to primary biliary cirrhosis (PBC), genome-wide association studies GWAS have been performed in patients of European ancestry and have shown the significant associations of IL12-related pathways, SPIB, IRF5-TNPO3, and 17q12-21. 21506939

2011
Entrez Id: 6689
Gene Symbol: SPIB
SPIB
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.620 GeneticVariation GWASDB Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis. 20639880

2010
Entrez Id: 6689
Gene Symbol: SPIB
SPIB
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.620 Biomarker CTD_human Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis. 20639880

2010
Entrez Id: 6689
Gene Symbol: SPIB
SPIB
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.620 GeneticVariation GWASCAT Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis. 20639880

2010
Entrez Id: 6689
Gene Symbol: SPIB
SPIB
CUI: C0008312
Disease: Primary biliary cirrhosis
Primary biliary cirrhosis 		0.620 SusceptibilityMutation ORPHANET