Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 Biomarker CTD_human Efficacy of laser capture microdissection plus RT-PCR technique in analyzing gene expression levels in human gastric cancer and colon cancer. 18652704

2008
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 AlteredExpression LHGDN AQUA analysis of thymidylate synthase reveals localization to be a key prognostic biomarker in 2 large cohorts of colorectal carcinoma. 18976010

2008
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 Biomarker CTD_human Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine. 19105824

2008
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 Biomarker CTD_human Thymidylate synthase haplotype is associated with tumor recurrence in stage II and stage III colon cancer. 18192902

2008
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 GeneticVariation BEFREE This study provides some support for associations between TS genotype and colon cancer tumor characteristics. 17290389

2007
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 Biomarker CTD_human Thymidylate synthase messenger RNA expression in plasma from patients with colon cancer: prognostic potential. 16609021

2006
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 AlteredExpression LHGDN Thymidylate synthase expression in colon carcinomas with microsatellite instability. 16675565

2006
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 Biomarker CTD_human Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer. 16284371

2005
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 AlteredExpression BEFREE Low TS protein levels in primary stage III colon tumours appeared to be associated with mucinous histology and low DPD protein levels with young age at time of randomisation. 16012177

2005
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 Biomarker CTD_human Furthermore, four of them (one each from TYMS and PKG1 and two from AICRT/1) possessed the ability to induce HLA-A2-restricted and peptide-specific CTLs cytotoxic to colon tumor cells in peripheral blood mononuclear cells of colon cancer patients. 15355913

2004
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 Biomarker BEFREE Isolation and characterization of a thymidylate synthase-deficient human colon tumor cell line. 10535743

1999
Entrez Id: 7298
Gene Symbol: TYMS
TYMS
CUI: C0009375
Disease: Colonic Neoplasms
Colonic Neoplasms 		0.360 Biomarker BEFREE Thymidylate synthase as a determinant of 5-fluoro-2'-deoxyuridine response in human colonic tumor cell lines. 2971871

1988