Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2551
Gene Symbol: GABPA
GABPA
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.060 GeneticVariation BEFREE In conclusion, NRF2 rs6721961 associated with CAD and severity of coronary atherosclerosis. 31332605

2020

Entrez Id: 2551
Gene Symbol: GABPA
GABPA
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.060 Biomarker BEFREE Nrf2/Keap1/ARE is one of the essential signaling pathways that can attenuate myocardial infarct size and preserve cardiac function after myocardial ischemia and reperfusion injury (MIRI). 30468811

2019

Entrez Id: 2551
Gene Symbol: GABPA
GABPA
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.060 GeneticVariation BEFREE Mechanism of Emulsified Isoflurane Postconditioning-Induced Activation of the Nrf2-Antioxidant Response Element Signaling Pathway During Myocardial Ischemia-Reperfusion: The Relationship With Reactive Oxygen Species. 31082959

2019

Entrez Id: 2551
Gene Symbol: GABPA
GABPA
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.060 PosttranslationalModification BEFREE Furthermore, GA increased the protein levels of Nrf-2 and HO-1 and downregulated the phosphorylation of IκB, and NF-κB p65 in ISO-induced MI. 29849452

2018

Entrez Id: 2551
Gene Symbol: GABPA
GABPA
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.060 Biomarker BEFREE Mechanism of myocardial ischemia/reperfusion-induced acute kidney injury through DJ-1/Nrf2 pathway in diabetic rats. 29104636

2017

Entrez Id: 2551
Gene Symbol: GABPA
GABPA
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis
0.060 AlteredExpression BEFREE Increased endoplasmic reticulum stress and Nrf2 repression in peripheral blood mononuclear cells of patients with stable coronary artery disease. 24373961

2014