Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 AlteredExpression BEFREE Predicting significance of COX-2 expression of peripheral blood monocyte in patients with coronary artery disease. 31700919

2019
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 AlteredExpression BEFREE The levels of COX-2 mRNA and protein in the plaque tissues, PBMCs and serum of patients with coronary atherosclerosis were significantly elevated compared with those in the corresponding control groups. 29725388

2018
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 GeneticVariation BEFREE The COX-2 rs20417 polymorphism and risk of coronary artery disease: evidence from 17,621 subjects. 24513487

2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 GeneticVariation BEFREE PTGS2 gene polymorphism -765G>C is associated with coronary artery disease: a meta-analysis. 24446343

2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 GeneticVariation BEFREE Interaction between COX-2 G-765C and smoking in relation to coronary artery disease in a Chinese Uighur population. 21091235

2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 GeneticVariation BEFREE Cox-2 gene polymorphism and IL-6 levels in coronary artery disease. 21574137

2011
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 GeneticVariation BEFREE Functional promoter polymorphism of cyclooxygenase-2 modulates the inflammatory response in stable coronary heart disease. 20332714

2010
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 GeneticVariation BEFREE A secondary aim was to replicate the interaction of PTGS2 rs20417 (-765G to C) with aspirin use on coronary heart disease risk observed in the Atherosclerosis Risk in Communities Study (ARIC). 19046748

2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 GeneticVariation BEFREE Cyclooxygenase-2 (COX-2) G-765C is a protective factor for coronary artery disease but not for ischemic stroke: a meta-analysis. 19631939

2009
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 GeneticVariation BEFREE Our objective was to study whether the functional C variant of the -765G-->C polymorphism in the human COX-2 gene associates with the severity of coronary atherosclerosis measured at the coronary artery level. 18385811

2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 GeneticVariation BEFREE Common polymorphisms of cyclooxygenase-2 and prostaglandin E2 receptor and increased risk for acute coronary syndrome in coronary artery disease. 18989535

2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.400 Biomarker CTD_human Effect of cyclooxygenase-2 inhibition with rofecoxib on endothelial dysfunction and inflammatory markers in patients with coronary artery disease. 14642682

2003