Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.070 AlteredExpression BEFREE However, the link between circulating levels of ACE2-Ang-(1-7)-Mas axis and coronary atherosclerosis in humans is not determined. 31359146

2020
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.070 AlteredExpression BEFREE Elevated plasma angiotensin converting enzyme 2 activity is an independent predictor of major adverse cardiac events in patients with obstructive coronary artery disease. 29897923

2018
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.070 Biomarker BEFREE Angiotensin-converting enzyme 2 inhibits high-mobility group box 1 and attenuates cardiac dysfunction post-myocardial ischemia. 26498282

2016
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.070 GeneticVariation BEFREE The influence of angiotensin-converting enzyme 2 gene polymorphisms on type 2 diabetes mellitus and coronary heart disease. 24142614

2013
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.070 AlteredExpression BEFREE In man, circulating ACE2 activity increases with coronary heart disease, as well as heart failure, and a large proportion of the variation in plasma ACE2 levels has been attributed to hereditary factors. 23013041

2013
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.070 GeneticVariation BEFREE Association study of ACE2 (angiotensin I-converting enzyme 2) gene polymorphisms with coronary heart disease and myocardial infarction in a Chinese Han population. 16822235

2006
Entrez Id: 59272
Gene Symbol: ACE2
ACE2
CUI: C0010054
Disease: Coronary Arteriosclerosis
Coronary Arteriosclerosis 		0.070 Biomarker BEFREE ACE2 deficiency impairs cardiac contractility and upregulates hypoxia-induced genes, suggesting a link with myocardial ischaemia. 15671045

2005