Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 406906
Gene Symbol: MIR122
MIR122
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
0.030 PosttranslationalModification BEFREE Our results suggest that oxidative stress-induced DNA methylation of miR-122 aggravates colitis targeting SELENBP1 partially by p65NF-<i>κ</i>B signaling and may promote the progression of CD. 31019652

2019

Entrez Id: 406906
Gene Symbol: MIR122
MIR122
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
0.030 GeneticVariation BEFREE In both diseases, rs17669 and rs11614913 (MIR122 and MIR196A2) seem to contribute to clinical phenotypes: ileal location in CD (odds ratio [OR] = 1.82, p = 0.03; OR = 0.51, p = 0.01), and left-sided extent in UC (OR = 0.43, p = 0.05; OR = 0.28, p = 0.002). 27718165

2017

Entrez Id: 406906
Gene Symbol: MIR122
MIR122
CUI: C0010346
Disease: Crohn Disease
Crohn Disease
0.030 AlteredExpression BEFREE Expression of miR-122 elevated in the macroscopically intact colonic regions of CD compared with controls and patients with UC. 26752469

2016