Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1490
Gene Symbol: CCN2
CCN2
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.240 Biomarker BEFREE Connective tissue growth factor (CTGF), a widely used biomarker, is involved in many diseases, such as diabetic retinopathy, diabetic nephropathy, and rheumatoid arthritis, and it is often over-expressed in human malignant tumors. 31288216

2019

Entrez Id: 1490
Gene Symbol: CCN2
CCN2
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.240 Biomarker BEFREE This paper summarizes the recent studies about CTGF on DR fibrosis for a comprehensive understanding of the role and mechanism of CTGF in PDR. 30225233

2018

Entrez Id: 1490
Gene Symbol: CCN2
CCN2
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.240 Biomarker BEFREE Importantly, these results also suggest that CTGF regulates changes in ECM molecules in DR. 22511849

2012

Entrez Id: 1490
Gene Symbol: CCN2
CCN2
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.240 Biomarker RGD Investigating structural and biochemical correlates of ganglion cell dysfunction in streptozotocin-induced diabetic rats. 19450451

2009

Entrez Id: 1490
Gene Symbol: CCN2
CCN2
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.240 Biomarker LHGDN Accumulation of NH2-terminal fragment of connective tissue growth factor in the vitreous of patients with proliferative diabetic retinopathy. 14988298

2004