Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0019061
Disease: Hemolytic-Uremic Syndrome
Hemolytic-Uremic Syndrome
0.330 Biomarker BEFREE The mediators (except IL-1β) are among the top six proinflammatory mediators found in the sera from patients with HUS in different studies. 29983334

2018

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0019061
Disease: Hemolytic-Uremic Syndrome
Hemolytic-Uremic Syndrome
0.330 Biomarker CTD_human The role of circulating immune complexes and biocompatibility of staphylococcal protein A immunoadsorption in mitomycin C-induced hemolytic uremic syndrome. 15384034

2004

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0019061
Disease: Hemolytic-Uremic Syndrome
Hemolytic-Uremic Syndrome
0.330 Biomarker BEFREE The data suggest that enterohemolysin, a pore-forming toxin, induces the production of IL-1beta, which is one of serum risk markers for HUS. 12135770

2002

Entrez Id: 3553
Gene Symbol: IL1B
IL1B
CUI: C0019061
Disease: Hemolytic-Uremic Syndrome
Hemolytic-Uremic Syndrome
0.330 Biomarker BEFREE We now document the ability of tetrapeptide-based inhibitors of interleukin 1beta-converting enzyme (ICE)-like caspase 1 and cysteine protease protein (CPP)-32-like caspase 3, two members of a novel class of cysteine proteases involved in final pathways to apoptosis, to block TTP/sporadic HUS plasma-mediated apoptosis. 9840908

1998