Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 PosttranslationalModification BEFREE IMD could attenuate the vascular collagen remodeling caused by angiotensin II-induced hypertension via inhibiting phosphorylation of Akt and MAPK. 30229842

2018

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 Biomarker BEFREE Remarkably, AKT1 was associated with hypertension in MEZs, but not in MAs. 30176313

2018

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 GeneticVariation BEFREE We use patient examples of sustained intracranial hypertension, systemic arterial hypotension, and plateau waves, as well as the retrospective analysis of 358 non-decompressive craniectomy (DC) TBI patients with high-frequency ICP and arterial blood pressure data, to explore the relationships of this new index, RAC, with AMP, ICP, CPP, RAP (correlation coefficient between AMP and ICP), pressure reactivity index (PRx), and pulse amplitude index (PAx). 29212405

2018

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 Biomarker BEFREE Transforming growth factor-beta1 upregulation triggers pulmonary artery smooth muscle cell proliferation and apoptosis imbalance in rats with hypoxic pulmonary hypertension via the PTEN/AKT pathways. 27297622

2016

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 Biomarker RGD Activation of the Renal PI3K/Akt/mTOR Signaling Pathway in a DOCA-Salt Model of Hypertension. 23323219

2012

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 AlteredExpression LHGDN Our data suggest that AKT is involved in endothelium dysfunction in hypertension. 15136501

2004

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.250 Biomarker BEFREE Our data suggest that AKT is involved in endothelium dysfunction in hypertension. 15136501

2004