Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.050 Biomarker BEFREE No significant association of proteinuria with IL-8 SNP or hypertension with selected eNOS and IL-8 SNPs was found. 31529205

2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.050 AlteredExpression BEFREE These findings suggest that Sulf2 is an up-regulatory factor in the additive action of CXCL8 via the AT<sub>1</sub> R pathway on Ang II-induced ET-1 expression in VSMCs under hypertension environment. 30470661

2019
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.050 AlteredExpression BEFREE Interestingly, high levels of IL-8 (P < 0.001) and VEGF (P < 0.05) were detected in the patients with GT who also suffered from hypertension. 28178402

2017
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.050 GeneticVariation BEFREE The risk for hypertension was increased in the presence of the T allele in IL8 rs1126647 (OR = 1.69, 95 % CI = 1.07-2.67, P = 0.024). 26387812

2015
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.050 Biomarker BEFREE The presence of type 2 diabetes associated with 3.2-fold increased PAI-1 expression (adjusted p=0.033), while the presence of hypertension associated with about 50% reduction of IL-8 and TIMP-1. 25496999

2015