Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 Biomarker BEFREE MMP-9 and TIMP-1 in placenta of hypertensive disorder complicating pregnancy. 31258700

2019
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 Biomarker BEFREE Curcumin modulates covalent histone modification and TIMP1 gene activation to protect against vascular injury in a hypertension rat model. 29285138

2017
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 GeneticVariation BEFREE The presence of type 2 diabetes associated with 3.2-fold increased PAI-1 expression (adjusted p=0.033), while the presence of hypertension associated with about 50% reduction of IL-8 and TIMP-1. 25496999

2015
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 Biomarker CTD_human Fosinopril and valsartan intervention in gene expression of Klotho, MMP-9, TIMP-1, and PAI-1 in the kidney of spontaneously hypertensive rats. 21051829

2010
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 Biomarker RGD Upregulation of tissue inhibitor of metalloproteases-1 (TIMP-1) and procollagen-N-peptidase in hypertension-induced renal damage. 17977875

2008
Entrez Id: 7076
Gene Symbol: TIMP1
TIMP1
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease 		0.540 AlteredExpression LHGDN Circulating pretreatment MMP-9 and TIMP-1 levels were significantly higher in patients with hypertension than in the normotensive controls (P =.0041 and P =.0166, respectively). 15363817

2004