Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6863
Gene Symbol: TAC1
TAC1
CUI: C0020649
Disease: Hypotension
Hypotension
0.500 Biomarker CTD_human Warm SPA-induced hyperthermia confers protection to rats against airway inflammation evoked by capsaicin and substance P. 20138590

2010

Entrez Id: 6863
Gene Symbol: TAC1
TAC1
CUI: C0020649
Disease: Hypotension
Hypotension
0.500 Biomarker RGD Thus our results show that the TRPV1, possibly via triggering release of SP which activates the NK1 and stimulates the sympathetic axis, plays a protective role against endotoxin-induced hypotension and mortality, suggesting that TRPV1 receptors are essential in protecting vital organ perfusion and survival during the endotoxic condition. 18337316

2008

Entrez Id: 6863
Gene Symbol: TAC1
TAC1
CUI: C0020649
Disease: Hypotension
Hypotension
0.500 Biomarker CTD_human The most sensitive sites where application of SP into the NTS evoked dose-dependent hypotension and bradycardia were at the level of the posterior tip of the area postrema (zero level) and at the level of the obex. 2445440

1987