Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
CUI: C0023283
Disease: Leishmaniasis, Cutaneous
Leishmaniasis, Cutaneous 		0.040 Biomarker BEFREE Blockade of the NLRP3 inflammasome in cell cultures from skin biopsies of patients with CL caused by L. braziliensis inhibited the release of IL-1β. 31357078

2019
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
CUI: C0023283
Disease: Leishmaniasis, Cutaneous
Leishmaniasis, Cutaneous 		0.040 Biomarker BEFREE Recently, NLRP3 inflammasome activation and IL-1β production have been associated with increased pathology in murine cutaneous leishmaniasis. 29246797

2018
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
CUI: C0023283
Disease: Leishmaniasis, Cutaneous
Leishmaniasis, Cutaneous 		0.040 AlteredExpression BEFREE GP63 could be associated with reduced NLRP3 inflammasome expression in CL and ML patients. 28397969

2017
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
CUI: C0023283
Disease: Leishmaniasis, Cutaneous
Leishmaniasis, Cutaneous 		0.040 Biomarker BEFREE These data reveal that Nlrp3 inflammasome-dependent IL-1β, associated with localized neutrophil recruitment, plays a crucial role in the development of a nonhealing form of cutaneous leishmaniasis in conventionally resistant mice. 26689285

2016