Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 25913
Gene Symbol: POT1
POT1
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia 		0.640 GeneticVariation BEFREE Tumor telomere length was significantly longer in UR-CLL than in UN-CLL (p = 0.009) and was associated with the POT1 mutation and survival. 29720177

2018
Entrez Id: 25913
Gene Symbol: POT1
POT1
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia 		0.640 GeneticVariation BEFREE Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy. 27226433

2016
Entrez Id: 25913
Gene Symbol: POT1
POT1
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia 		0.640 GeneticVariation BEFREE We performed whole-exome sequencing of 66 CLL families, identifying 4 families where loss-of-function mutations in protection of telomeres 1 (<i>POT1</i>) co-segregated with CLL. 27528712

2016
Entrez Id: 25913
Gene Symbol: POT1
POT1
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia 		0.640 GeneticVariation GWASCAT A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia. 24292274

2014
Entrez Id: 25913
Gene Symbol: POT1
POT1
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia 		0.640 GeneticVariation GWASDB A genome-wide association study identifies multiple susceptibility loci for chronic lymphocytic leukemia. 24292274

2014
Entrez Id: 25913
Gene Symbol: POT1
POT1
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia 		0.640 Biomarker BEFREE The identification of POT1 as a new frequently mutated gene in CLL may facilitate novel approaches for the clinical management of this disease. 23502782

2013
Entrez Id: 25913
Gene Symbol: POT1
POT1
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia 		0.640 SomaticCausalMutation ORPHANET The identification of POT1 as a new frequently mutated gene in CLL may facilitate novel approaches for the clinical management of this disease. 23502782

2013
Entrez Id: 25913
Gene Symbol: POT1
POT1
CUI: C0023434
Disease: Chronic Lymphocytic Leukemia
Chronic Lymphocytic Leukemia 		0.640 CausalMutation CGI