Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.050 AlteredExpression BEFREE Tanshinone IIA induces apoptosis and autophagy in acute monocytic leukemia via downregulation of PI3K/Akt pathway. 31217869

2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.050 Biomarker BEFREE Dueling for dual inhibition: Means to enhance effectiveness of PI3K/Akt/mTOR inhibitors in AML. 29276026

2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.050 Biomarker BEFREE Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells. 29559471

2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.050 AlteredExpression BEFREE Constitutive activation of the PI3K/AKT signaling pathway is found in ~50-70% of AML patients. 29143813

2017
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0023465
Disease: Acute monocytic leukemia
Acute monocytic leukemia 		0.050 AlteredExpression BEFREE Aberrant activation of the PI3K/mTOR pathway promotes resistance to sorafenib in AML. 26999641

2016