DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Moyamoya Disease ×

Gene: HLA-DRB1 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	3123
Gene Symbol:	HLA-DRB1

HLA-DRB1

CUI:	C0026654
Disease:	Moyamoya Disease

Moyamoya Disease

0.320

GeneticVariation

BEFREE

HLA-DRB1*04:10 is a risk allele and HLA-DRB1*04:10-HLA-DQB1*04:02 a risk haplotype for MMD.

31412073

2019

Entrez Id:	3123
Gene Symbol:	HLA-DRB1

HLA-DRB1

CUI:	C0026654
Disease:	Moyamoya Disease

Moyamoya Disease

0.320

Biomarker

BEFREE

In addition, in 22 patients with MMD a higher frequency of HLA-DRB1*03 (P (c) < 0.001) was observed when compared with controls.

22234791

2012

Entrez Id:	3123
Gene Symbol:	HLA-DRB1

HLA-DRB1

CUI:	C0026654
Disease:	Moyamoya Disease

Moyamoya Disease

0.320

Biomarker

GENOMICS_ENGLAND

Paediatric stroke: genetic insights into disease mechanisms and treatment targets.

21349441

2011