Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 102723407
Gene Symbol: LOC102723407
LOC102723407
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.070 GeneticVariation BEFREE Since MGUS generally precedes MM, these data suggest origins of MGUS and MM with IGHV gene mutational ICV from the same GC B-cell, arising via a distinctive pathway. 25929340

2015

Entrez Id: 102723407
Gene Symbol: LOC102723407
LOC102723407
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.070 Biomarker BEFREE Within the MM sample, 37 IGHV genes were expressed, with 98.9% of all immunoglobulin sequences using the same IGHV gene as the MM clone and 83.0% exhibiting exact nucleotide sequence identity in the IGHV and heavy chain complementarity determining region 3 (HCDR3). 22522905

2012

Entrez Id: 102723407
Gene Symbol: LOC102723407
LOC102723407
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.070 AlteredExpression BEFREE Analysis of the expressed immunoglobulin variable region heavy chain gene products in paraproteins from Iranian patients with multiple myeloma. 11033458

2000

Entrez Id: 102723407
Gene Symbol: LOC102723407
LOC102723407
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.070 Biomarker BEFREE Although several studies have demonstrated somatically mutated immunoglobulin variable region genes in multiple myeloma, it is unclear if myeloma cells are derived from GCs or post-GC memory B cells. 9547329

1998

Entrez Id: 102723407
Gene Symbol: LOC102723407
LOC102723407
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.070 GeneticVariation BEFREE Somatic hypermutation of immunoglobulin variable region genes: focus on follicular lymphoma and multiple myeloma. 9602371

1998

Entrez Id: 102723407
Gene Symbol: LOC102723407
LOC102723407
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.070 GeneticVariation BEFREE Comparable gene structure of the immunoglobulin heavy chain variable region between multiple myeloma and normal bone marrow lymphocytes. 8892685

1996

Entrez Id: 102723407
Gene Symbol: LOC102723407
LOC102723407
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma
0.070 GeneticVariation BEFREE Distinctive features of immunoglobulin heavy chain variable region gene rearrangement in multiple myeloma. 7950918

1994