Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.330 AlteredExpression BEFREE HSP27 expression was increased in patients with MM compared with healthy control subjects, and the expression was increased as the cancer progressed (P<0.05). 31322176

2019
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.330 AlteredExpression BEFREE In conclusion, these results indicate that 17-AAG-mediated induction of HSP70 and HSP27 expression can be attenuated by Act D and therefore can potentially improve the clinical treatment of multiple myeloma. 19383903

2009
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.330 Biomarker CTD_human These data demonstrate that Hsp27 inhibits the release of Smac, and thereby confers Dex resistance in MM cells. 12855565

2003
Entrez Id: 3315
Gene Symbol: HSPB1
HSPB1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.330 AlteredExpression LHGDN These data demonstrate that Hsp27 inhibits the release of Smac, and thereby confers Dex resistance in MM cells. 12855565

2003