Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.140 AlteredExpression BEFREE Microhomology-mediated end joining drives complex rearrangements and over expression of MYC and PVT1 in multiple myeloma. 31221783

2019
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.140 Biomarker BEFREE In <i>in vitro</i> function assays, we found that PVT1 inhibition suppressed MM cell proliferation and induced MM cell apoptosis (<i>p</i> < 0.05). 30393487

2018
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.140 GeneticVariation GWASCAT Genome-wide association analysis of chronic lymphocytic leukaemia, Hodgkin lymphoma and multiple myeloma identifies pleiotropic risk loci. 28112199

2017
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.140 GeneticVariation BEFREE These findings suggest that PVT1 rearrangements may represent a novel molecular paradigm underlying the pathology of 8q24 rearrangement-positive multiple myeloma. 22869583

2012
Entrez Id: 5820
Gene Symbol: PVT1
PVT1
CUI: C0026764
Disease: Multiple Myeloma
Multiple Myeloma 		0.140 Biomarker BEFREE A chromosomal translocation (Tx) that interrupts the transcription of either c-Myc or Pvt 1 is the principal lesion in many B cell malignancies including Burkitt's Lymphoma (BL), AIDs-NHL, mouse plasmacytoma (Pct) and possibly multiple myeloma (MM). 9308229

1997