Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 Biomarker BEFREE Finally, we identified the class 1A phosphatidylinositol 3-kinase (PI3K) as the critical signaling mediator of CD28 that regulates cell metabolism and amplify specific inflammatory T cell phenotypes in MS. 31212712

2019
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 Biomarker BEFREE Preclinical evaluation of the PI3K/Akt/mTOR pathway in animal models of multiple sclerosis. 29492193

2018
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 Biomarker BEFREE Although the PI3K/Akt/mTOR pathway was found to be activated by cannabinoids in several immune and non-immune cells, currently, there is no data about the effects of CBD in the PI3K/Akt/mTOR activity in MS. 27890794

2017
Entrez Id: 5290
Gene Symbol: PIK3CA
PIK3CA
CUI: C0026769
Disease: Multiple Sclerosis
Multiple Sclerosis 		0.040 Biomarker BEFREE By using specific inhibitory drugs, we also identify the phosphatidylinositol 3 kinase (PI3K) as the critical regulator of CD28 proinflammatory functions in MS. 24412596

2014