Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0027859
Disease: Acoustic Neuroma
Acoustic Neuroma
0.030 AlteredExpression BEFREE These findings implicate aberrant activation of the PI3K/AKT/mTOR pathway as a molecular mechanism of pathogenesis in VS and suggest inhibition of this pathway as a potential treatment strategy. 25245477

2014

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0027859
Disease: Acoustic Neuroma
Acoustic Neuroma
0.030 Biomarker BEFREE Because PTEN regulates signaling through the growth-promoting phosphoinositide 3-kinase/AKT pathway, our findings suggest that miR-21 may be a suitable molecular target for therapies aimed specifically at reducing VS growth. 20856158

2010

Entrez Id: 207
Gene Symbol: AKT1
AKT1
CUI: C0027859
Disease: Acoustic Neuroma
Acoustic Neuroma
0.030 Biomarker BEFREE Immunohistochemical analysis using antibodies to activated phosphorylated-AKT was performed on 14 VS tissue sections. 18199958

2008