Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2180
Gene Symbol: ACSL1
ACSL1
CUI: C0028754
Disease: Obesity
Obesity
0.520 AlteredExpression BEFREE Consistent with the cell culture system, muscle-specific SENP2 overexpression led to a marked increase in the mRNA levels of CPT1b and ACSL1 and thereby in FAO in the skeletal muscle, which ultimately alleviated high-fat diet-induced obesity and insulin resistance. 25784542

2015

Entrez Id: 2180
Gene Symbol: ACSL1
ACSL1
CUI: C0028754
Disease: Obesity
Obesity
0.520 Biomarker CTD_human Orchestrated downregulation of genes involved in oxidative metabolic pathways in obese vs. lean high-fat young male consumers. 20882379

2011

Entrez Id: 2180
Gene Symbol: ACSL1
ACSL1
CUI: C0028754
Disease: Obesity
Obesity
0.520 Biomarker BEFREE We quantified mRNA expression of subcutaneous adipose tissue fatty-acid-handling proteins (ALBP, KLBP, FATP1, FATP4, CD36, ACS1) in 17 monozygotic twin-pairs with a range of intra-pair differences (Delta) in BMI and detailed measures of obesity and insulin resistance, allowing influences of genetic and non-genetic factors to be distinguished. 15168018

2004

Entrez Id: 2180
Gene Symbol: ACSL1
ACSL1
CUI: C0028754
Disease: Obesity
Obesity
0.520 Biomarker RGD Marked enhancement of acyl-CoA synthetase activity and mRNA, paralleled to lipoprotein lipase mRNA, in adipose tissues of Zucker obese rats (fa/fa). 1543733

1992