Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 27035
Gene Symbol: NOX1
NOX1
CUI: C0028754
Disease: Obesity
Obesity 		0.010 Biomarker BEFREE In summary, the current data support a main role for Nox1-derived O<sub>2</sub><sup>.-</sup> in kidney vascular oxidative stress and renal endothelial dysfunction in obesity, while reduced endothelial Nox4 expression associated to decreased H<sub>2</sub>O<sub>2</sub> generation and H<sub>2</sub>O<sub>2</sub>-mediated vasodilatation might hinder Nox4 protective renal effects thus contributing to kidney injury. 31563085

2020