Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.340 Biomarker BEFREE Our recent results suggest that local injection of a TRPV4 agonist is a potential treatment for osteoarthritis (OA). 31622206

2019
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.340 AlteredExpression BEFREE TRPV4 was upregulated in ALCT-induced OA articular cartilage, and we found that administration of a TRPV4 inhibitor attenuated cartilage degeneration. 31055086

2019
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.340 Biomarker BEFREE Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis. 30629441

2019
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.340 AlteredExpression BEFREE At the protein level, TRPV4 was over expressed in early OA sfMPCs, while KCNJ12 and KCNMA1 were unchanged between normal and early OA sfMPCs. 26632350

2016
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis 		0.340 Biomarker CTD_human Our data raise the possibility that TRPV4 may also have a role in age- or injury-related osteoarthritis. 21964574

2011