Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7507
Gene Symbol: XPA
XPA
CUI: C0033300
Disease: Progeria
Progeria 		0.030 Biomarker BEFREE We previously reported that XPA mislocalized to the progerin-induced DNA double-strand break (DSB) sites, blocking DSB repair, which led to DSB accumulation, DNA damage responses, and early replication arrest in HGPS. 28515154

2017
Entrez Id: 7507
Gene Symbol: XPA
XPA
CUI: C0033300
Disease: Progeria
Progeria 		0.030 Biomarker BEFREE In a reaction unique to HGPS and RD cells these accessible DSB termini bind Xeroderma pigmentosum group A (XPA) protein which excludes normal binding by DNA DSB repair proteins. 19851476

2009
Entrez Id: 7507
Gene Symbol: XPA
XPA
CUI: C0033300
Disease: Progeria
Progeria 		0.030 Biomarker LHGDN Involvement of xeroderma pigmentosum group A (XPA) in progeria arising from defective maturation of prelamin A. 17848622

2008