Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 Biomarker BEFREE The current aim was to further characterize biological responses and mechanisms underpinning CXCL8-promoted progression of PTEN-depleted prostate cancer, focusing on characterizing the potential interplay between CXCL8 and other disease-promoting chemokines resident within the prostate tumor microenvironment. 24970800

2014
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 AlteredExpression LHGDN Depletion of intracellular zinc increases expression of tumorigenic cytokines VEGF, IL-6 and IL-8 in prostate cancer cells via NF-kappaB-dependent pathway. 18615482

2008
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 AlteredExpression LHGDN Chemotherapy-induced CXC-chemokine/CXC-chemokine receptor signaling in metastatic prostate cancer cells confers resistance to oxaliplatin through potentiation of nuclear factor-kappaB transcription and evasion of apoptosis. 18780829

2008
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 AlteredExpression LHGDN Translationally regulated C/EBP beta isoform expression upregulates metastatic genes in hormone-independent prostate cancer cells. 18512730

2008
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 Biomarker LHGDN Osteopontin and interleukin-8 expression is independently associated with prostate cancer recurrence. 18593988

2008
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 AlteredExpression LHGDN Regulation of interleukin-8 expression in human prostate cancer cells by insulin-like growth factor-I and inflammatory cytokines. 17513150

2007
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 Biomarker CTD_human Interleukin-8 signaling promotes translational regulation of cyclin D in androgen-independent prostate cancer cells. 17606477

2007
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 Biomarker CTD_human Diverse effects of zinc on NF-kappaB and AP-1 transcription factors: implications for prostate cancer progression. 16606632

2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 AlteredExpression LHGDN Characterization of TGF-beta-regulated interleukin-8 expression in human prostate cancer cells. 16541418

2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 Biomarker BEFREE Interleukin 8 (IL-8) and vascular endothelial growth factor (VEGF) are two cytokines promoting prostate tumor growth and angiogenesis. 16530725

2006
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 AlteredExpression LHGDN Serum interleukin-8 is elevated in men with prostate cancer and bone metastases. 15453805

2004
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8
CUI: C0033578
Disease: Prostatic Neoplasms
Prostatic Neoplasms 		0.400 AlteredExpression LHGDN Bombesin stimulates nuclear factor kappa B activation and expression of proangiogenic factors in prostate cancer cells. 12839933

2003