|
HLA-DRB1
|
Psoriasis
|
0.100 |
Biomarker |
BEFREE |
Human leukocyte antigen-DRB1*0102 and *0306 are significantly associated with psoriasis.
|
30251731 |
2018 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
Biomarker |
BEFREE |
A number of SNPs in HLA-DRB1 have been found being associated with the risk of psoriasis, however it is unclear that metylation status within HLA-DRB1 in psoriasis.
|
27713139 |
2017 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
GeneticVariation |
BEFREE |
We genotyped for HLA-DRB1 locus 1228 patients with AIDs-213 with Systemic Lupus Erythematosus (SLE), 166 with Psoriasis or Psoriatic Arthritis (Ps + PsA), 153 with Rheumatoid Arthritis (RA), 67 with Systemic Sclerosis (SSc), 536 with Multiple Sclerosis (MS), and 93 with Myasthenia Gravis (MG) and 282 unrelated controls.
|
26605347 |
2015 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
GeneticVariation |
BEFREE |
No differences related to family history of psoriasis were observed in HLA-DRB1*1501 polymorphism.
|
23834030 |
2013 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
Biomarker |
BEFREE |
Our findings confirm HLA-C*06 and DRB1*07 as the most important genetic risk factors for psoriasis.
|
23184486 |
2013 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
Biomarker |
BEFREE |
HLA-Cw*06 and HLA-DRB1*07 are associated with patients with PsA having type I psoriasis, suggesting that the primary association is with age of onset of psoriasis.
|
17728335 |
2008 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
GeneticVariation |
BEFREE |
Patients with PsA carrying both HLA-Cw6 and HLA-DRB1*07 alleles have a less severe course of arthritis.
|
17223660 |
2007 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
Biomarker |
BEFREE |
HLA Cw*0602 and DRB1*0701 were represented in different reports, and the former was related mainly to psoriasis type I.
|
17309450 |
2007 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
GeneticVariation |
BEFREE |
As we compared type I and type II psoriasis with control group, B*57, Cw6 and DRB1*07 alleles were more significant in patients with type I psoriasis.
|
16532100 |
2006 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
GeneticVariation |
LHGDN |
Association between psoriasis vulgaris and MHC-DRB, -DQB genes as a contribution to disease diagnosis.
|
15908298 |
2005 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
Biomarker |
BEFREE |
(iv) These associated haplotypes with PV were not different by sex, except that the frequency of DRB1*0701/02-DQB1*0303 (P < 0.0001, OR = 10.14) was higher in male patients with psoriasis.
|
15245541 |
2004 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
GeneticVariation |
BEFREE |
Type I psoriasis showed a significant association with the DRB1*0701 [P < 0.00001; relative risk (RR) = 5.83], DQA1*0201 (P < 0.00001; RR = 6.12), DQB1*0201 (P = 0.0006; RR = 3.29) and DQB1*0303 alleles (P = 0.0008; RR = 7.51).
|
12653713 |
2003 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
Biomarker |
BEFREE |
HLA-A*207, -B*4601, -Cw*01, -DRB1*09, -DQB1*0303 (AH46.1), HLA-A*01-B*57-Cw*0602-DRB1*07-DQB1*0303 (AH57.1), and HLA-A*30, -B*13, -Cw*0602, -DRB1*07, and -DQB1*02 (AH13.1) were identified as high-risk major histocompatibility complex (MHC) halotypes for psoriasis patients in the early onset group in north-eastern Thais.
|
12100686 |
2002 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
GeneticVariation |
BEFREE |
HLA-A33-B44-Cw*1401-DRB1*13-DQA1* 01-DQB1*06-DPB1*0401 was defined as a protective haplotype for psoriasis.
|
10651991 |
2000 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
Biomarker |
BEFREE |
This data demonstrated two susceptible haplotypes: HLA-A1-B57-DRB1*0701-DQA1*0201-DQB1*0303 (AH57.1) and HLA-A2-B46-DRB1*0901-DQA1*0301-DQB1*0303 (AH46.1) for type I psoriasis in the Thai population.
|
9820604 |
1998 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
GeneticVariation |
BEFREE |
EH-57.1+ individuals therefore carry a 26 times higher risk of developing type I psoriasis than individuals who are EH-57.1-negative Further analysis of individual HLA alleles revealed that within EH-57.1, HLA class I antigens (Cw6-B57) were associated to a much higher extent with type I psoriasis than the HLA class II alleles (DRB1*0701-DQA1*0201-DQB1* 0303).
|
8618009 |
1996 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
GeneticVariation |
BEFREE |
We conclude that disease association in type I psoriasis is associated with the extended haplotype HLA-B57, -Cw6, -DRB1*0701/2, -DQA1*0201, -DQB1*0303.
|
8002377 |
1994 |
|
HLA-DRB1
|
Psoriasis
|
0.100 |
GeneticVariation |
BEFREE |
Oligonucleotide typing reveals association of type I psoriasis with the HLA-DRB1*0701/2, -DQA1*0201, -DQB1*0303 extended haplotype.
|
8496614 |
1993 |