Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.090 Biomarker BEFREE This article is part of a special issue entitled: PI3K-AKT-FOXO axis in psoriasis. 30483877

2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.090 Biomarker BEFREE Interestingly, some of the identified proteins and pathways with significantly different modifications, such as S100A9 and the PI3K-Akt signaling pathway, have been previously reported to be associated with psoriasis. 31229693

2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.090 Biomarker BEFREE PSORI-CM02 ameliorates psoriasis in vivo and in vitro by inducing autophagy via inhibition of the PI3K/Akt/mTOR pathway. 31401494

2019
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.090 Biomarker BEFREE PI3K/AKT/mTOR activation and autophagy inhibition plays a key role in increased cholesterol during IL-17A mediated inflammatory response in psoriasis. 29432814

2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.090 Biomarker BEFREE PI3K-Akt signaling pathway and five other pathways had close correlation with the pathogenesis of psoriasis and could deserve further research. 29537306

2018
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.090 Biomarker BEFREE We recently reported that the PI3K/Akt/mTOR pathway that is frequently deregulated in many malignancies is also clinically relevant for psoriasis. 27393705

2017
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.090 Biomarker BEFREE However, the expression of PTEN and the correlation between PTEN and PI3K/Akt have not been investigated in patients with psoriasis. 24168180

2014
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.090 Biomarker BEFREE This novel observation provides the scope to develop new therapeutics targeting PI3K/Akt/mTOR signaling pathway in autoimmune diseases like psoriasis and rheumatoid arthritis. 22840496

2012
Entrez Id: 5294
Gene Symbol: PIK3CG
PIK3CG
CUI: C0033860
Disease: Psoriasis
Psoriasis 		0.090 Biomarker BEFREE Taken together, these data indicate that PI3Kδ and/or PI3Kγ inhibitors should be considered for treating IL-17-driven diseases, such as psoriasis. 23024273

2012