Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 GeneticVariation BEFREE A meta-analysis was performed to evaluate the associations of polymorphisms in the ANTXR2 gene with AS. 30255098

2018
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 GeneticVariation BEFREE The association between ANTXR2 rs4333130 and AS was independent of HLA-B27 status. 26590821

2016
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 AlteredExpression BEFREE ANTXR2 messenger RNA (mRNA) expression was significantly higher in the AS group than in the control group (P = 0.039). 26728147

2016
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 Biomarker BEFREE This study aimed to investigate the possible mechanisms of ANTXR2 involved in AS pathogenesis. 25736362

2015
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 GeneticVariation BEFREE We also used data for AS patients from previous genome-wide association studies to investigate the AS risk locus ANTXR2 for its putative effect in AAU. 25200001

2015
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 GeneticVariation BEFREE Further studies are required to clarify the role played by these ANTXR2 variants in AS. 25169729

2014
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 Biomarker BEFREE No association was observed between AS and ANTXR2 or IL-1R2 in present study, indicating that the polymorphisms in the ANTXR2 and IL-1R2 gene may not be regarded as major contributors to AS susceptibility in Chinese Han population. 20652271

2012
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 Biomarker BEFREE Thus, the six SNPs of ANTXR2 are not associated with AS in our Chinese Shandong Han population. 22118297

2012
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 GeneticVariation BEFREE Here we report the identification of three variants in the RUNX3, LTBR-TNFRSF1A and IL12B regions convincingly associated with ankylosing spondylitis (P < 5 × 10(-8) in the combined discovery and replication datasets) and a further four loci at PTGER4, TBKBP1, ANTXR2 and CARD9 that show strong association across all our datasets (P < 5 × 10(-6) overall, with support in each of the three datasets studied). 21743469

2011
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 GeneticVariation GWASDB Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. 21743469

2011
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 GeneticVariation GWASCAT Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. 21743469

2011
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 Biomarker CTD_human Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. 21743469

2011
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 GeneticVariation BEFREE Investigators from the Australo-Anglo-American Spondyloarthritis Consortium have reported additional genes associated with ankylosing spondylitis (AS) susceptibility including IL1R2, ANTXR2, and gene deserts at 2p15 and 21q22. 21041274

2011
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 Biomarker CTD_human Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. 20062062

2010
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 GeneticVariation GWASCAT Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. 20062062

2010
Entrez Id: 118429
Gene Symbol: ANTXR2
ANTXR2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.500 GeneticVariation GWASDB Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. 20062062

2010