Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) and undifferentiated spondylarthritis (uSpA) are related inflammatory diseases affecting the spine and joints with infections among possible etiological factors. 31802207

2020

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is an inflammatory rheumatic disease with increased bone mass in the main sites of inflammation. 31074089

2020

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is an autoimmune disease with high disability rate, and it is sometimes difficult to distinguish from generalized osteoarthritis (GOA). 31794766

2020

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is a systemic inflammatory disease, and cardiac dysfunction has not been clearly described clinically. 30418346

2020

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is an inflammatory arthritis in which males have a higher risk of developing progressive axial disease than females. 31599089

2020

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is a prototype of chronic inflammatory arthritis termed seronegative spondyloarthropathies that typically affects the joints. 31711818

2020

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) and gout are common inflammatory arthropathies. 31630236

2020

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE In summary, we present a reliable real-time PCR protocol for HLA-B*27 screening directly in whole blood supporting fast clarification of the presence of ankylosing spondylitis or other spondyloarthritides in suspected cases. 31749313

2020

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is a chronic inflammatory joint disease that involves the entheses, causing inflammatory pain and functional impairments. 29787813

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized with heterotopic ossification of the axis joints ligaments, resulting in joint disability. 31726387

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) refers to a type of arthritis manifested with chronic inflammation of spine joints. microRNAs (MiRNAs) have been identified as new therapeutic targets for inflammatory diseases. 31111563

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Considered together, the ability of both protective and disease-associated HLA-B27 allotypes to form homodimers and the failure of HLA-B*27:03 to form homodimers challenge the role of HLA-B27 homodimers in AS pathoetiology. 31740583

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE The mechanism of pathological osteogenesis in Ankylosing spondylitis (AS) is largely unknown. 31024000

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 GeneticVariation BEFREE We aimed to present a systematic evaluation of 47 non Major Histocompatibility Complex (MHC) Ankylosing Spondylitis (AS) susceptibility loci which have been initially discovered through Caucasian Genome-wide association studies (GWASs) in Han Chinese. 31523044

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is the second most common cause of inflammatory arthritis worldwide affecting the axial skeleton. 31124320

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by axial arthritis. 30777138

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is a chronic inflammatory rheumatic disease. 31432140

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is a chronic inflammatory disease which effects cervical posture of patients. 31292936

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is prototype of SpA. 31741083

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is a type of rheumatic inflammatory disease. miRNAs participate in the process of regulating inflammatory response and bone differentiation. 31217850

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is an inflammatory autoimmune disorder that manifested with sacroiliitis at its early stage and developed extensive inflammation with syndesmophytes of the lumbar, thoracic and cervical spines at its later stage. 31130248

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is a type of chronic progressive inflammatory disease, which often causes significant damage to the patients on the physical function, labour ability and quality of life. 31397536

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Background Ankylosing spondylitis (AS) is a chronic rheumatological condition affecting sacroiliac joint and spine and occurs more often in younger patients than in the elderly population. 31754591

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Ankylosing spondylitis (AS) is a form of arthritis that can lead to fusion of vertebrae and sacroiliac joints following syndesmophyte formation. 31360722

2019

Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis
0.500 Biomarker BEFREE Several other HLA-B and non-B molecules have been associated with AS, although their role in the pathogenesis is unknown. 31712904

2019