Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.160 Biomarker BEFREE <b>Methods:</b> PBMCs from 18 patients with active AS and 18 healthy individuals were separated by Ficoll-Hypaque density gradient centrifugation and cultured in the presence of muramyl dipeptide (MDP), as NOD2 ligand. 30265175

2018
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.160 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.160 GeneticVariation BEFREE The association with HLA-B27 is less strong in IBD-associated SpA than in Idiopathic Ankylosing Spondylitis (AS) and there is some evidence for an association between gut inflammation in SpA and CD related CARD15 mutations. 19530505

2009
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.160 GeneticVariation BEFREE Subjects with AS were genotyped for the R702W, G908R, and Leu1007fsinsC variants of CARD15 using mass array MALDI-TOF mass spectrometry. 15468360

2004
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.160 GeneticVariation BEFREE We conclude that the insertion 3020insC mutation and the G2722C missense mutation in the CARD15 gene are not involved in the susceptibility to AS. 12595906

2003
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.160 GeneticVariation BEFREE The 3 most common CD NOD2 mutations do not contribute to disease susceptibility to AS, and therefore do not explain the susceptibility locus for AS in chromosome 16q. 12508397

2003
Entrez Id: 64127
Gene Symbol: NOD2
NOD2
CUI: C0038013
Disease: Ankylosing spondylitis
Ankylosing spondylitis 		0.160 GeneticVariation BEFREE No association was demonstrated between NOD2 variants and primary AS, or between other variants of NOD2 and either UC or CD spondylarthritis. 12115195

2002