|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
Biomarker |
BEFREE |
Correlation between visual acuity and human leukocyte antigen DRB1*04 in patients with Vogt-Koyanagi-Harada disease.
|
31699055 |
2019 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis of Vogt-Koyanagi-Harada syndrome identifies two new susceptibility loci at 1p31.2 and 10q21.3.
|
25108386 |
2014 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
GeneticVariation |
BEFREE |
We identified three loci associated with VKH syndrome susceptibility (IL23R-C1orf141, rs117633859, P(combined) = 3.42 × 10(-21), odds ratio (OR) = 1.82; ADO-ZNF365-EGR2, rs442309, P(combined) = 2.97 × 10(-11), OR = 1.37; and HLA-DRB1/DQA1, rs3021304, P(combined) = 1.26 × 10(-118), OR = 2.97).
|
25108386 |
2014 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
Biomarker |
BEFREE |
Our meta-analysis confirmed the association between VKH and HLA-DR4/DRB1*04, found the strength of association is different in different ethnic groups, and identified HLA-DRB1*0404, 0405 and 0410 as risk sub-alleles while 0401 as protective sub-allele.
|
25382027 |
2014 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
GeneticVariation |
BEFREE |
The HLA-DRB1*0405 allele is the main susceptibility allele for VKHS.
|
23567866 |
2013 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
Biomarker |
BEFREE |
We investigated the contribution of HLA-A*, -B*, -C*, -DRB1*, and -DQB1* genes, belonging to the human leukocyte antigen (HLA), to the expression of VKH and we analyzed the influence of gender on the HLA association.
|
21964432 |
2011 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
GeneticVariation |
BEFREE |
The HLA-DRB1 association with susceptibility to VKH syndrome seems weaker in Indian patients compared to Japanese or Hispanic patients, suggesting a different non-HLA immunogenetic background in Indian VKH patients.
|
20216938 |
2010 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
Biomarker |
BEFREE |
HLA-DRB1 among patients with Vogt-Koyanagi-Harada disease in Saudi Arabia.
|
19756183 |
2009 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
GeneticVariation |
BEFREE |
In silico prediction of binding of putative antigenic peptides to HLA-DRB1 alleles in Vogt-Koyanagi-Harada disease.
|
15927531 |
2005 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
GeneticVariation |
BEFREE |
HLA-DRB1 and -DQB1 alleles in mestizo patients with Vogt-Koyanagi-Harada's disease in Southern California.
|
15603876 |
2004 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
GeneticVariation |
LHGDN |
HLA-DRB1 and -DQB1 alleles in mestizo patients with Vogt-Koyanagi-Harada's disease in Southern California.
|
15603876 |
2004 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
GeneticVariation |
BEFREE |
The DRB1*04-DQA1*03 haplotype is a marker of increased SO susceptibility and severity, as in Vogt-Koyanagi-Harada disease, which also has similar clinicopathological and HLA associations.
|
11222331 |
2001 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
Biomarker |
BEFREE |
These results suggest that HLA-DRB1*0405 itself or HLA-DRB1*0405-DQA1*0302-DQB1*0401 haplotype is greatly increased and may play the most important role in the development and the clinical course of VKH syndrome in Korean patients.
|
10682969 |
2000 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
Biomarker |
BEFREE |
The high frequency of DRB1*04 was dependent on DRB1*0405 in VKH, but on DRB1*0410 in ITP.
|
9572996 |
1998 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
GeneticVariation |
BEFREE |
HLA-DRB1*0405 is the predominant allele in Brazilian patients with Vogt-Koyanagi-Harada disease.
|
9548078 |
1998 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
GeneticVariation |
BEFREE |
Complete association of the HLA-DRB1*04 and -DQB1*04 alleles with Vogt-Koyanagi-Harada's disease.
|
8026985 |
1994 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
GeneticVariation |
BEFREE |
Influence of HLA-DRB1 gene variation on the clinical course of Vogt-Koyanagi-Harada disease.
|
7906684 |
1994 |
|
HLA-DRB1
|
Uveomeningoencephalitic Syndrome
|
0.200 |
Biomarker |
BEFREE |
HLA-DRB1 typing of Vogt-Koyanagi-Harada's disease by PCR-RFLP and the strong association with DRB1*0405 and DRB1*0410.
|
7908535 |
1994 |