Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0042900
Disease: Vitiligo
Vitiligo
0.140 Biomarker BEFREE Our studies have identified three specific alleles, HLA-A*33:01, HLA-B*44:03, and HLA-DRB1*07:01, to be significantly increased in vitiligo patients as compared with controls in both the initial study on North Indians (N=1,404) and the replication study in Gujarat (N=355) cases, establishing their positive association with vitiligo. 21833019

2012

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0042900
Disease: Vitiligo
Vitiligo
0.140 GeneticVariation GWASDB Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo. 22561518

2012

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0042900
Disease: Vitiligo
Vitiligo
0.140 Biomarker BEFREE The DRB1*07 showed significant association with vitiligo in the study population. 21241376

2011

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0042900
Disease: Vitiligo
Vitiligo
0.140 GeneticVariation GWASDB Genome-wide association study for vitiligo identifies susceptibility loci at 6q27 and the MHC. 20526339

2010

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0042900
Disease: Vitiligo
Vitiligo
0.140 GeneticVariation GWASDB Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo. 20410501

2010

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0042900
Disease: Vitiligo
Vitiligo
0.140 GeneticVariation BEFREE Furthermore, we also found suggestive epistatic effect between rs2269577 and HLA-DRB1*07 allele on the development of vitiligo (p = 0.033). 19543371

2009

Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
CUI: C0042900
Disease: Vitiligo
Vitiligo
0.140 GeneticVariation BEFREE By investigating a group of 39 unrelated adults suffering from vitiligo it was found that alleles HLA-DRB1*0701, -DQB1*0201, and -DPB1*1601 differed in their frequencies in comparison to those observed in the healthy population. 9653015

1999