Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0085413
Disease: Polycystic Kidney, Autosomal Dominant
Polycystic Kidney, Autosomal Dominant 		0.040 Biomarker BEFREE Antagonization of ET-1 may hopefully be a novel therapy for slowing progression of kidney damage in ADPKD. 30990410

2019
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0085413
Disease: Polycystic Kidney, Autosomal Dominant
Polycystic Kidney, Autosomal Dominant 		0.040 GeneticVariation BEFREE Recent studies have reported that EDN1 and EDNRA polymorphisms can influence the age of onset of end-stage renal disease in ADPKD. 21894000

2011
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0085413
Disease: Polycystic Kidney, Autosomal Dominant
Polycystic Kidney, Autosomal Dominant 		0.040 GeneticVariation BEFREE We examined the influence of three single-nucleotide polymorphisms of the ET-1 gene (EDN1)--K198N, 3A/4A, and T-1370G--on the progression of ADPKD towards end-stage renal disease (ESRD). 16943682

2006
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
CUI: C0085413
Disease: Polycystic Kidney, Autosomal Dominant
Polycystic Kidney, Autosomal Dominant 		0.040 Biomarker BEFREE As a first step in investigating the potential role of endothelin-1 (ET1) and its receptors (ETA and ETB) in the pathophysiology of progression in ADPKD, we have studied their expression and cellular localisation in ADPKD kidney. 12629276

2003