Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
CUI: C0085669
Disease: Acute leukemia
Acute leukemia 		0.050 GeneticVariation BEFREE NOTCH1 mutation in a female with myeloid/NK cell precursor acute leukemia. 20730882

2010
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
CUI: C0085669
Disease: Acute leukemia
Acute leukemia 		0.050 GeneticVariation BEFREE The ETV6-NCOA2 fusion may define a novel subgroup of acute leukemia with T-lymphoid and myeloid features, which is associated with a high prevalence of NOTCH1 mutations. 18281529

2008
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
CUI: C0085669
Disease: Acute leukemia
Acute leukemia 		0.050 AlteredExpression BEFREE These results demonstrated that overexpression/enhanced kinase activity of BCR/ABL and altered expression of Notch1 induces acute leukemia in a transgenic model for CML. 18193087

2008
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
CUI: C0085669
Disease: Acute leukemia
Acute leukemia 		0.050 Biomarker BEFREE Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias. 18184405

2007
Entrez Id: 4851
Gene Symbol: NOTCH1
NOTCH1
CUI: C0085669
Disease: Acute leukemia
Acute leukemia 		0.050 Biomarker BEFREE Truncation of Notch1 has been shown to cause a subtype of acute leukemia, and activation of Notch4 has been associated with mammary and salivary gland carcinomas of mice. 12539049

2003