Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10818
Gene Symbol: FRS2
FRS2
CUI: C0205824
Disease: Liposarcoma, Dedifferentiated
Liposarcoma, Dedifferentiated 		0.040 Biomarker BEFREE Recent studies identified consistent amplification of FRS2 gene in atypical lipomatous tumor/well-differentiated liposarcoma and dedifferentiated liposarcoma. 30001240

2018
Entrez Id: 10818
Gene Symbol: FRS2
FRS2
CUI: C0205824
Disease: Liposarcoma, Dedifferentiated
Liposarcoma, Dedifferentiated 		0.040 Biomarker BEFREE This study indicates that FGFR inhibitors have therapeutic potential in the treatment of DDLPS with amplified FRS2. 27409346

2016
Entrez Id: 10818
Gene Symbol: FRS2
FRS2
CUI: C0205824
Disease: Liposarcoma, Dedifferentiated
Liposarcoma, Dedifferentiated 		0.040 Biomarker BEFREE Attenuation of FRS2 protein in FU-DDLS-1 and LiSa-2 cell lines decreased the phosphorylated extracellular signal-regulated kinase 1/2 and AKT and repressed cell proliferation. 23393200

2013
Entrez Id: 10818
Gene Symbol: FRS2
FRS2
CUI: C0205824
Disease: Liposarcoma, Dedifferentiated
Liposarcoma, Dedifferentiated 		0.040 AlteredExpression BEFREE Real time PCR showed FRS2 mRNA transcriptional upregulation in WDLS (n = 19) and DDLS (n = 13) but not in lipoma (n = 5) and normal fat (n = 9). 21793095

2011