DisGeNET - a database of gene-disease associations

Source: ALL

Disease: Medullomyoblastoma ×

Gene: PTCH1 ×

Results per page

Gene

Disease

Variant

Source

Association Type

Semantic type

Protein Class

Disease Class

Type

Original DB

Consequence

DSI _g

DPI _g

pLI

EI _gda

EL _gda

Score _gda

PMID

PMID Year

AF_EXOME

Num. PMIDs

Num. SNPs_gda

AF_GENOME

Gene

Disease

Score _gda

Association Type

Original DB

Sentence supporting the association

PMID

PMID Year

Entrez Id:	5727
Gene Symbol:	PTCH1

PTCH1

CUI:	C0205833
Disease:	Medullomyoblastoma

Medullomyoblastoma

0.300

Biomarker

CTD_human

Antitumor effects of a combined 5-aza-2'deoxycytidine and valproic acid treatment on rhabdomyosarcoma and medulloblastoma in Ptch mutant mice.

19155313

2009

Entrez Id:	5727
Gene Symbol:	PTCH1

PTCH1

CUI:	C0205833
Disease:	Medullomyoblastoma

Medullomyoblastoma

0.300

Biomarker

CTD_human

Bortezomib reverses a post-translational mechanism of tumorigenesis for patched1 haploinsufficiency in medulloblastoma.

19213072

2009

Entrez Id:	5727
Gene Symbol:	PTCH1

PTCH1

CUI:	C0205833
Disease:	Medullomyoblastoma

Medullomyoblastoma

0.300

Biomarker

CTD_human

Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.

18347096

2008