Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0278601
Disease: Inflammatory Breast Carcinoma
Inflammatory Breast Carcinoma 		0.090 GeneticVariation BEFREE We observed recurrent variants of known IBC-related mutations, and the most commonly mutated genes in DCIS were PIK3CA (34.4%) and TP53 (18.4%). 31420779

2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0278601
Disease: Inflammatory Breast Carcinoma
Inflammatory Breast Carcinoma 		0.090 GeneticVariation BEFREE TP53 and ERBB2 mutations were significantly more prevalent in inflammatory breast cancer than in non-inflammatory breast cancer (P < 0.01). 28243898

2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0278601
Disease: Inflammatory Breast Carcinoma
Inflammatory Breast Carcinoma 		0.090 Biomarker BEFREE This study reviews the advances in molecular understanding of IBC and focuses on the efficacy of therapies that target the epidermal growth factor pathway and angiogenesis as well as early investigational therapies involving RhoC and TP53. 20133255

2010
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0278601
Disease: Inflammatory Breast Carcinoma
Inflammatory Breast Carcinoma 		0.090 Biomarker BEFREE Our objectives are to clarify molecular alterations of HER-2/neu and p53 in IBC and to investigate the prognostic factors. 16755113

2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0278601
Disease: Inflammatory Breast Carcinoma
Inflammatory Breast Carcinoma 		0.090 GeneticVariation BEFREE The role of p53 mutations as a prognostic factor and therapeutic target in inflammatory breast cancer. 16563093

2006
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0278601
Disease: Inflammatory Breast Carcinoma
Inflammatory Breast Carcinoma 		0.090 GeneticVariation BEFREE LCIS demonstrated a low grade/favorable biophenotype that was not significantly different in cases with and without synchronous IBC (ER 98%, PgR 84%, c-erbB-24%, p53 19% and proliferation rate 2%). 15830138

2005
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0278601
Disease: Inflammatory Breast Carcinoma
Inflammatory Breast Carcinoma 		0.090 AlteredExpression BEFREE We retrospectively analyze the expression of p53 as a prognostic marker to predict pathological complete response and survival in patients with IBC. 15448010

2004
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0278601
Disease: Inflammatory Breast Carcinoma
Inflammatory Breast Carcinoma 		0.090 GeneticVariation BEFREE The prevalence of the TP53 mutation was much higher in IBC than in the two other types of cancer (57% vs 30). 12386822

2002
Entrez Id: 7157
Gene Symbol: TP53
TP53
CUI: C0278601
Disease: Inflammatory Breast Carcinoma
Inflammatory Breast Carcinoma 		0.090 Biomarker BEFREE Twenty-seven cases of inflammatory breast cancer were screened for the presence of the p53 protein by immunocytochemical methods using a monoclonal antibody directed against the p53 protein. 1353891

1992