Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 AlteredExpression BEFREE Together, our initial findings demonstrate that CGA suppresses ESCC progression, downregulates the expression of BMI1 and SOX2, and provide an anti-tumor candidate for ESCC therapy. 31707349

2020

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 Biomarker BEFREE We previously found that autoantibodies against a panel of six tumor-associated antigens (p53, NY-ESO-1, MMP-7, Hsp70, PRDX6 and Bmi-1) may aid in early detection of esophageal squamous cell carcinoma. 30426295

2019

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 Biomarker BEFREE Therefore, combined targeting of BMI1 and Mel18 may serve as a promising therapeutic strategy for sensitizing ESCC to chemotherapy. 31186712

2019

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 Biomarker BEFREE In addition, BMI-1 was positively related to tumour size and lymph node metastases and negatively to the overall survival of ESCC patients. 29207170

2018

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 Biomarker BEFREE WITHDRAWN: Expression and clinicopathological significance of Mel-18 and Bmi-1 in oesophageal squamous cell carcinoma. 28485167

2017

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 Biomarker BEFREE Expression and Clinicopathological Significance of Mel-18 and Bmi-1 in Esophageal Squamous Cell Carcinoma. 28425347

2017

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 Biomarker BEFREE These results indicated that Bmi-1 and PADI4 positively regulate carcinogenesis and progression of ESCC. 28599437

2017

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 Biomarker BEFREE In the present study, our findings confirm miR-218 as a tumor suppressor and identify BMI1 as a novel target of miR-218 in ESCC. 25999024

2015

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 AlteredExpression BEFREE In this study, we examined the expression of Bmi-1 and miR-203 in ESCC SP and non-SP (NSP) cells. 24219349

2014

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 Biomarker BEFREE Using the radioresistant KYSE-150R esophageal squamous cell carcinoma (ESCC) model, which was derived from KYSE-150 parental cells using FIR, the role of Bmi-1 in mediating the radioadaptive response of ESCC cells to RT was investigated. 22842564

2012

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 AlteredExpression BEFREE High expression of Bmi-1, a key regulatory component of the polycomb repressive complex-1, has been associated with many solid and hematologic malignancies including esophageal squamous cell carcinoma. 23078618

2012

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 AlteredExpression BEFREE Aberrant EZH2 and BMI1 protein expression was observed in 19 (14.0%) and 23 (16.9%), respectively, of the 136 ESCCs. 21165554

2011

Entrez Id: 648
Gene Symbol: BMI1
BMI1
Squamous cell carcinoma of esophagus
0.100 AlteredExpression BEFREE Multivariate analysis suggested that Bmi-1 expression was an independent prognostic marker for ESCC patients. 20809956

2010