Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3815
Gene Symbol: KIT
KIT
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.140 GeneticVariation BEFREE The findings also suggest that targeting the SPHK/S1P axis may provide an alternative to tyrosine kinase inhibitors, alone or in combination, for the treatment of aggressive mastocytosis and other hematological malignancies associated with the D816V-KIT mutation. 29643855

2018
Entrez Id: 3815
Gene Symbol: KIT
KIT
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.140 GeneticVariation CLINVAR An update on molecular genetics of gastrointestinal stromal tumours. 16731599

2006
Entrez Id: 3815
Gene Symbol: KIT
KIT
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.140 AlteredExpression BEFREE Our data indicate that OCNs mRNA and OCN protein is expressed in c-KIT positive neoplastic stem cells in hematological malignancies. 16387359

2006
Entrez Id: 3815
Gene Symbol: KIT
KIT
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.140 PosttranslationalModification BEFREE Mutations of KIT receptor tyrosine kinase are involved in the constitutive activation and development of human hematologic malignancies. 15339674

2004
Entrez Id: 3815
Gene Symbol: KIT
KIT
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.140 Biomarker BEFREE This study was designed to analyze the mutation of D835 of FLT3, which corresponds to D816 of c-KIT, in a large series of human hematologic malignancies. 11290608

2001
Entrez Id: 3815
Gene Symbol: KIT
KIT
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.140 GeneticVariation CLINVAR STI571 inactivation of the gastrointestinal stromal tumor c-KIT oncoprotein: biological and clinical implications. 11526490

2001