Source: ALL

Gene Disease Score gda Association Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 648
Gene Symbol: BMI1
BMI1
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.060 AlteredExpression BEFREE In this work we demonstrate for the first time that in CML the BMI1 protein is co-expressed with BCR-ABL1 only in the cytoplasm of the CD26+ precursors; on the contrary, in other hematological malignancies where BMI1 is commonly expressed (follicular lymphoma, essential thrombocytemia, acute myeloid leukemia), it was not co-localized with CD26 or, obviously, with BCR-ABL1. 30574454

2018
Entrez Id: 648
Gene Symbol: BMI1
BMI1
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.060 Biomarker BEFREE The BMI1 proto‑oncogene (Bmi‑1) promotes the development and progression of hematologic malignancies and of several types of solid tumors. 28849237

2017
Entrez Id: 648
Gene Symbol: BMI1
BMI1
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.060 Biomarker BEFREE The oncogene, Bmi-1, promotes the development of hematologic malignancies and many solid tumors. 27600678

2016
Entrez Id: 648
Gene Symbol: BMI1
BMI1
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.060 AlteredExpression BEFREE High expression of Bmi-1, a key regulatory component of the polycomb repressive complex-1, has been associated with many solid and hematologic malignancies including esophageal squamous cell carcinoma. 23078618

2012
Entrez Id: 648
Gene Symbol: BMI1
BMI1
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.060 AlteredExpression BEFREE Here, we quantitatively examined BMI-1 expression level in samples from patients with acute myeloid leukemia (AML) and other hematologic malignancies. 16105758

2005
Entrez Id: 648
Gene Symbol: BMI1
BMI1
CUI: C0376545
Disease: Hematologic Neoplasms
Hematologic Neoplasms 		0.060 AlteredExpression BEFREE BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas. 11289106

2001